- Dow 861
- Assistant Professor, Civil, Environmental, and Geospatial Engineering
- PhD, Public Health, University of Illinois at Chicago
- MS, Environmental Engineering, Beijing Technology and Business University, China
- BS, Bioengineering, Chang'an University, China
Before joining Michigan Tech, Dr. Jiehong Guo was a senior researcher at the University of Minnesota Twin Cities. She has previously worked in Indiana University Bloomington as a Postdoctoral Research Associate. Her research focuses on two parts. One is to identify biomarkers of DNA damage caused by carcinogens using mass spectrometric approaches. Another part is to develop and apply analytical methods to measure persistent, bioaccumulative and toxic (PBT) pollutants in various environmental matrices, evaluate the magnitude of environmental pollution, and examine the fate and transport of PBT chemicals in the environment. Dr. Guo has published over 35 peer reviewed papers in Environmental Science and Technology, Chemical Research in Toxicology, Journal of Hazardous Materials, etc.
Links of Interest
- Qualitative and quantitative mass spectrometry application
- Persistent, bioaccumulative, and toxic pollutants (PBTs) monitoring
- Fate and transport of PBTs in aquatic environment
- Biomarkers of DNA damage induced by carcinogens
- Jiehong Guo, Stephen S. Hecht. DNA damage in human oral cells induced by use of e-cigarettes. Drug Testing and Analysis, 2022; 1- 9. doi:10.1002/dta.3375
- Jiehong Guo, Joshua Ikuemonisan, Dorothy K. Hatsukami, Stephen S. Hecht. Liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry analysis of apurinic/apyrimidinic sites in oral cell DNA of cigarette smokers, e-cigarette users and nonsmokers. Chemical Research in Toxicology, 34 (12), 2540-2548, 2021.
- Jiehong Guo, Haoqing Chen, Pramod Upadhyaya, Yingchun Zhao, Robert J. Turesky, Stephen S. Hecht. Mass spectrometric quantitation of apurinic/apyrimidinic sites in tissue DNA of rats exposed to tobacco-specific nitrosamines and in lung and leukocyte DNA of cigarette smokers and nonsmokers. Chemical Research in Toxicology, 33 (9), 2475–2486, 2020.
- Jiehong Guo, Zhuona Li, Prabha Ranasinghe, Karl J. Rockne, Neil C. Sturchio, John P. Giesy, An Li. Halogenated flame retardants in sediments from the Upper Laurentian Great Lakes: Implications to long-range transport and evidence of long-term transformation. Journal of Hazardous Materials, 384, 121346, 2020.
- Jiehong Guo, William Stubbings, Kevin Romanak, Linh V. Nguyen, Liisa Jantunen, Lisa Melymuk, Victoria Arrandale, Miriam L. Diamond and Marta Venier. An Alternative Flame Retardant, 2,4,6-Tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ), in an E-waste Recycling Facility and House Dust in North America, Environmental Science and Technology, 52 (6), 3599-3607, 2018.
- NIH/NCI R03 CA- 259652 Guo, J (PI) 01/31/2022 – 12/31/2024
- Carcinogenic tobacco-specific nitrosamines induction of apurinic/apyrimidinic sites in DNA of human oral cells
- Cigarette smoke, smokeless tobacco and electronic cigarettes may induce DNA damage and cause lung and oral cavity cancer. We will quantify DNA damage in oral cells of humans exposed to different types of tobacco products in order to provide an effective biomarker of human exposure to carcinogens. Our goal is to advance our understanding of tobacco-induced cancer and ultimately develop effective strategies for cancer prevention