Chemical biology: development of novel molecular probes for DNA sequencing analysis
and disease gene discovery
Medicinal chemistry: development of new imaging and therapeutic agents towards cancer
and cardiovascular disease; Design and synthesis of novel prodrugs of peptides and
peptide mimetics.
Patents
Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible
terminators. PCT Int. Appl. (2008), 96pp. WO 2008069973
SBS (DNA sequencing by synthesis) using chemically cleavable 3'-O-allyl-dNTP-allyl-fluorophore
fluorescent nucleotide analogues. PCT Int. Appl. (2007), 52pp. WO 2007053719
Synthesis of four-color 3'-O-allyl modified photocleavable fluorescent nucleotides
and their incorporation into DNA using polymerase. PCT Int. Appl. (2007), 112pp. WO
2007053702
Preparation of 1,3-Dioxane Derivatives Having Protein Kinase C Inhibitory Activity
and their Therapeutic Use. US Pub.App.20050043396
1,3-dioxane derivatives, its preparation and their therapeutic use. CN Pub. App 1450064
