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Jeremy Goldman



  • Professor, Biomedical Engineering
  • Affiliated Professor, Materials Science and Engineering
  • Affiliated Professor, Department of Biological Sciences

Research Interests

  • The biology and physiology of the lymphatic and blood vascular systems including vascular regeneration, remodeling and pathology
  • Vascular biomaterials, including polymeric, natural, and metallic, for vascular repair and regeneration


  • owen PK, Seitz JM, Guillory RJ II, Braykovich JP, Zhao S, Goldman J, Drelich JW. Evaluation of Wrought Zn-Al Alloys (1, 3, and 5 wt% Al) Through Mechanical and In Vivo Testing for Stent Applications. Accepted. Journal of Biomedical Materials Research - Part B. 2017 Jan 27. doi: 10.1002/jbm.b.33850
  • Zhao S, McNamara CT, Bowen PK, Verhun N, Braykovich JP, Goldman J, Drelich J. Structural characteristics and in vitro biodegradation of a novel Zn-Li alloy prepared by induction melting and hot rolling. Metallurgical and Materials Transactions A. 48 (3), 1204-1215. 2016.
  • Guillory RJ II, Bowen PK, Hopkins S, Shearier ER, Earley E, Gillette A, Aghion E, Bocks M, Drelich J, Goldman J. Corrosion characteristics dictate the long-term inflammatory profile of degradable zinc arterial implants. ACS Biomaterials Science and Engineering. 2 (12), 2355-2364. 2016.
  • Drelich AJ, Bowen PK, LaLonde L, Goldman J, Drelich JW. Importance of oxide film in endovascular biodegradable zinc stents. Surface Innovations. 4(3):1-1. 2016.
  • McCarthy C, Guillory RJ II, Goldman J, Frost MC. Transition metal mediated release of nitric oxide (NO) on the surface of stents via corrosion products. ACS Applied Materials and Interfaces. 2016 Apr 27;8(16):10128-35.
  • Bowen PK, Shearier ER, Zhao S, Guillory RJ II, Zhao F, Goldman J, Drelich JW. Biodegradable metals for cardiovascular stents: from clinical concerns to recent Zn – alloys. Advanced Healthcare Materials. 2016 May;5(10):1121-40.
  • Shearier E, Bowen P, Weilue H, Drelich A, Drelich J, Goldman J, Zhao F. In Vitro Cytotoxicity, Adhesion, and Proliferation of Human Vascular Cells Exposed to Zinc. ACS Biomaterials Science and Engineering. 2016; 2 (4):634−642.
  • McCarthy C, Goldman J, Frost M. Synthesis and Characterization of the Novel Nitric Oxide (NO) Donating Compound, S-nitroso-N-acetyl-D-penicillamine Derivatized Cyclam (SNAP-Cyclam). ACS Applied Materials and Interfaces. 2016 Mar 9;8(9):5898-905.
  • Levy GK, Ventura Y, Goldman J, Vago R, Aghion E. Cytotoxic characteristics of biodegradable EW10X04 Mg alloy after Nd coating and subsequent heat treatment. Materials Science and Engineering C. 2016 May 1;62:752-61.
  • Hakimi O, Ventura Y, Goldman J, Vago R, Aghion E. Porous biodegradable EW62 medical implants resist tumor cell growth. Materials Science and Engineering C. 2016 Apr 1;61:516-25.
  • Bowen PK, McNamara C, Mills O, Drelich J, Goldman J. FIB-TEM study of magnesium corrosion products after 14 days in the murine artery. ACS Biomaterials Science & Engineering. 2015; 1 (10), 919-926.
  • Connor M, Danielle A, Joda D, Curtis T, Bowen PK, Guillory RJ, Liu SQ, Feng Z, Frost M, Goldman J. Fabrication and Short-Term In Vivo Performance of a Natural Elastic Lamina - Polymeric Hybrid Vascular Graft. ACS Applied Materials & Interfaces. 2015; 7 (30):16202–16212.
  • Bowen PK, Guillory RJ, Shearier ER, Seitz JM, Drelich J, Bocks M, Zhao F, Goldman J. Metallic Zinc Exhibits Optimal Biocompatibility for Bioabsorbable Endovascular Stents. Materials Science and Engineering C. 56 (2015) 467–472.
  • Seitz JS, Durisin M, Goldman J, and Drelich J. Recent Advances in Biodegradable Metals for Medical Sutures: A Critical Review. Advanced Healthcare Materials. 2015 Sep;4(13):1915-36.
  • Aghion E, Jan L, Meshi L, and Goldman J. Increased corrosion resistance of the AZ80 magnesium alloy by rapid solidification. Accepted. Journal of Biomedical Materials Research - Part B. 2015 Nov;103(8):1541-8
  • Lynch LL, Mendez U, Waller AB, Gillette A, Guillory RJ, and Goldman J. Fibrosis Worsens Chronic Lymphedema in Rodent Tissues. Am J Physiol Heart Circ Physiol. 2015 May;308(10):H1229-36
  • Hakimi O, Aghion E, and Goldman J. Improved stress corrosion cracking resistance of a novel biodegradable EW62 magnesium alloy by rapid solidification, in simulated electrolytes. Material Science and Engineering C. 2015 Jun;51:226-32.
  • Bowen PK, Drelich A, Drelich J, and Goldman J. Rates of in vivo (arterial) and in vitro biocorrosion for pure magnesium. Journal of Biomedical Materials Research - Part A. 2015 Jan;103(1):341-9.
  • Aghion E, Guingui I, and Goldman J. Corrosion behavior of nano/sub-micron F401 titanium alloy. Advanced Engineering Materials. 2014 Jul;17(5):626-631.
  • Bowen PK, Drelich J, and Goldman J. Magnesium in the murine artery: Probing the products of corrosion. Acta Biomaterialia. 2014 Mar;10(3):1475-83.
  • Bowen PK, Drelich J, and Goldman J. A new in vitro-in vivo correlation for bioabsorbable magnesium stents from mechanical behavior. Materials Science and Engineering C. 33 (2013) 5064–5070.
  • Bowen PK, Drelich J, and Goldman J. Zinc Exhibits Ideal Physiological Corrosion Behavior for Bioabsorbable Stents. Advanced Materials. 2013 May 14;25(18):2577-82.
  • Keim A, Slis J, Mendez U, Brown E, Burmeister Y, Tsolaki N, Gailing O, and Goldman J. Amelioration of Experimental Lymphedema by the Multicomponent Medication Lymphomyosot. Lymphat Res Biol. 2013 Jun;11(2):81-92. doi: 10.1089/lrb.2012.0024.
  • Mendez U, Stroup EM, Lynch LL, Waller AB, and Goldman J. A Chronic and Latent Lymphatic Insufficiency Follows Recovery from Acute Lymphedema in the Rat Foreleg. Am J Physiol Heart Circ Physiol. 2012 Nov;303(9):H1107-13.
  • Roberts MA, Gilbert RJ, and Goldman J. Increased Hyaluronan Expression at Distinct Time Points in Acute Lymphedema. Lymphatic Research and Biology. 2012 Sep;10(3):122-8.
  • Bowen PK, Drelich J, Buxbaum RE, Rajachar RM, Stinson JS, and Goldman J. New in vitro and in vivo approaches in evaluating metallic candidates for bioabsorbable stents. Emerging Materials Research, 2012. Read More
  • Barron M, Goldman J, Tsai CJ, and Donahue S. Perfusion flow enhances osteogenic gene expression and the infiltration of osteoblasts and endothelial cells into three-dimensional calcium phosphate scaffolds. International Journal of Biomaterials. Volume 2012, Article ID 915620. doi:10.1155/2012/915620.
  • Bowen PK, Gelbaugh JA, Mercier PJ, Goldman J, and Drelich JW. Tensile testing as a novel method for quantitatively evaluating bioabsorbable material degradation. Journal of Biomedical Materials Research – Part B. 2012 Nov;100(8):2101-13.
  • Mendez U, Brown EM, Ongstad EL, Slis JR, and Goldman J. Functional Recovery of Fluid Drainage Precedes Lymphangiogenesis in Acute Murine Foreleg Lymphedema. Am J Physiol Heart Circ Physiol. 302: H2250–H2256, 2012.
  • Pierson D, Edick J, Tauscher A, Pokorney E, Bowen P, Gelbaugh J, Stinson J, Getty H, Lee CH, Drelich J, Goldman J. A simplified in vivo approach for evaluating the bioabsorbable behavior of candidate stent materials. Journal of Biomedical Materials Research – Part B. 2012:100B:58–67.
  • Sripathi SR, He W, Um JY, Moser T, Dehnbostel S, Song L, Kindt K, Goldman J, Frost MC, and Jahng WJ. Nitric Oxide Leads to Cytoskeletal Reorganization in the Retinal Pigment Epithelium Under Oxidative Stress. Accepted – Advances in Bioscience and Biotechnology, 2012. doi:10.4236/abb.2012.
  • Bouta EM, McCarthy CW, Keim A, Wang HB, Gilbert RJ, and Goldman J. Biomaterial Guides for Lymphatic Endothelial Cell Alignment and Migration. Acta Biomaterialia. March 2011; 7(3):1104-1113.
  • Ongstad EL, Bouta EM, Roberts JE, Uzarski JS, Gibbs SE, Sabel MS, Cimmino VM, Roberts MA, Goldman J. Lymphangiogenesis-Independent Resolution of Experimental Edema. Am J Physiol Heart Circ Physiol. 2010 Jul;299(1):H46-54. Epub 2010 Mar 5. Read More
  • Uzarski J, Drelles MB, Gibbs SE, Ongstad EL, Goral JC, McKeown KK, Raehl AM, Roberts MA, Pytowski B, Smith MR, Goldman J. The resolution of lymphedema by interstitial flow in the mouse tail skin. Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1326-34.
  • Goldman J, Conley KA, Raehl A, Bondy DM, Pytowski B, Swartz MA, Rutkowksi JM, Jaroch DB, Ongstad EL. Regulation of Lymphatic Capillary Regeneration by Interstitial Flow in Skin. Am J Physiol Heart Circ Physiol. May 2007;292:H2176-H2183.Read More
  • Goldman J, Rutkowski JM, Shields JD, Pasquier MC, Cui Y, Schmökel HG, Hicklin DJ, Pytowski B, and Swartz MA. Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis. FASEB J. 2007 Apr;21(6):1003-12.
  • Goldman J, Zhong L, Liu SQ. Negative Regulation of Vascular Smooth Muscle Cell Migration by Blood Shear Stress. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H928-38
  • Rutkowski JM, Moya M, Johannes J, Goldman J, Swartz MA. Secondary lymphedema in the mouse tail: Lymphatic hyperplasia, VEGF-C upregulation, and the protective role of MMP-9. Microvasc Res. 2006 Nov;72(3):161-71.Read More
  • Goldman J, Le TX, Skobe M, and Swartz MA. Overexpression of VEGF-C causes transient hyperplasia but not increased lymphangiogenesis in regenerating skin. Circulation Research. 96:1193-1199, 2005.
  • Pytowski B, Goldman J, Persaud K, Wu Y, Witte L, Hicklin D, Skobe M, Boardman K.C., and Swartz M.A. Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralization antibody. J of the National Cancer Institute. 97:14-21, 2005.
  • Goldman J, Zhong L, and Liu S.Q. Degradation of a-actin filaments in venous smooth muscle cells in response to mechanical stretch. Am J Physiol Heart Circ Physiol. 284: H1839-H1847, 2003.
  • Liu SQ, Ran YY, Tang D, Li YC, Goldman J,and Zhong L. A possible role of initial cell death due to mechanical stretch in the regulation of subsequent cell proliferation in experimental vein grafts. Biomechanics and Modeling in Mechanobiology. 1:17-27, 2002.
  • Liu SQ, Zhong L, and Goldman J. Control of the shape of a thrombus-neointima-like structure by blood shear stress. Journal of Biomechanical Engineering. 124(1): 30-36, 2002.
  • Liu SQ, Zhong L, Jian ZL, Goldman J, Moore MM. Regulation of Shear Dependent Vascular Smooth Muscle Cell Migration By Tyrosine Kinase Signaling Pathways. In Advances in Biomechanics, Zhu C., and Lun M ed., Springer-Verlag, Berlin, 2001, pp. 62-73.
  • Moore MM, Goldman J, Patel A, Chien S, and Liu SQ. Role of tensile stress and strain in the induction of cell death in experimental vein grafts. Journal of Biomechanics 34(3): 289-297, 2001.
  • Liu SQ and Goldman J. Role of blood shear stress in the regulation of vascular smooth muscle cell migration. IEEE Transactions on Biomedical Engineering, 48(4): 474-483, 2001.