Chemical Advanced Resolution Methods (ChARM) Lab

Contact

ChARM is part of the Microanalytical Shared Facility overseen by the Vice President for Research Office. Michael Gretz is the founding director of ChARM, overseeing gas chromatography, inductively coupled mass spectrometry, and general microscopy equipment. Lynn Mazzoleni extended the mass spectrometry capabilities of ChARM by securing National Science Foundation funds for an Orbitrap Elite mass spectrometer and associated equipment. She also relocated her research LCQ Fleet MS instrument and liquid chromatograph to ChARM for shared use. Sangyoon Han joined the team to extend the microscopy capabilities with major upgrades to the confocal microscope. 

Simeon Schum is responsible for general laboratory management, operation, and maintenance of the 2d-LC and ultrahigh resolution Orbitrap Elite MS and LC/MS instruments, and associated equipment in ChARM to benefit users from multiple disciplines on- and off-campus. In addition to managing the laboratory, he assists in the design of analytical strategies, training users, conducting data analysis, and generating reports. A portion of his time is available for advanced research tasks on a project-by-project basis; salary support is required for non-routine duties.

Staff

Simeon Schum

Simeon K. Schum

  • Research Specialist, Chemistry

Research Interests

  • Research applications involving ultrahigh resolution Orbitrap Elite mass spectrometry, tandem mass spectrometry, and other mass spectrometry measurements
  • Computational methods for analysis of ultrahigh resolution mass spectrometry data
  • Method development for liquid chromatography, ion chromatography, gas chromatography
  • Analysis of environmental and biological complex mixtures

Faculty

Michael R. Gretz

  • Professor, Biological Sciences
  • Director, Chemical Advanced Resolution Methods Laboratory

Research Interests

  • Algal Extracellular Polymers and Biocomposites - Regulation of Biogenesis

Sang Yoon Han

  • Assistant Professor, Biomedical Engineering
  • Affiliate Assistant Professor in Mechanical Engineering - Engineering Mechanics
  • Advisor, Korean Student Association

Research Interests

Lab Web Page

Research Interests

  • Mechanobiology
  • Traction force by a living cell
  • Cell adhesion and migration
  • Image data modeling
  • Machine learning
  • BioMEMS

Lynn R. Mazzoleni

  • Associate Professor, Chemistry

Research Interests

  • Understanding the identities, occurrence, and transformation of aerosol organic compounds
  • Identifying organic aerosol constituents from a variety of atmospheric environments
  • Exploration of new LC column chemistries with ultrahigh pressure pumps for fast and thorough separations
  • Aqueous reaction pathways