Marina Tanasova

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Synthesis of molecular probes for evaluating substrate selection by carbohydrate transporters
Development of platforms for tumor imaging and drug delivery
Design and synthesis of bioreductively-activated DNA repair inhibitors

Altered Minor Groove Hydrogen Bonds in DNA Block Transcription Elongation by T7 RNA Polymerase, ChemBioChem, 2015
Sensing Remote Chirality: Stereochemical Determination of β-, γ-, and δ-Chiral Carboxylic Acids, Angew. Chem. Int. Ed. 2015 Read More
Quantification of Pyrophosphate as a Universal Approach to Determine Polymerase Activity and Assay Polymerase Inhibitors, Anal. Biochem. 2015
"Fluorescent THF-Based Fructose Analogue Exhibits Fructose-Dependent Uptake", ChemBioChem, 2013 Read More
"Chemistry and Biology of Acylfulvenes: Sesquiterpene-Derived Antitumor Agents", Chem. Rev. 2012 Read More

Evaluating therapeutic potential of fructose transport targeting for cancer therapy and prevention.
Development of fructose metabolism inhibitors.
Development of carbohydrate transport specific drug delivery platforms
Development of fluorescent assays for evaluating carbohydrate transport activity and screening carbohydrate transport and metabolism inhibitors
Synthesis and evaluation of bioreductively-activated pharmacophores