Nazmiye Bihter Yapici

Nazmiye Bihter Yapici


  • Postdoctoral Associate, Physics
  • PhD, Chemistry, Michigan Technological University, Houghton, MI (2013)
  • MSc, Chemistry, Middle East Technical University, Ankara, Turkey (2008)
  • BSc, Chemistry, Middle East Technical University, Ankara, Turkey (2006)


Enthusiastic, innovative, and award-winning professional with broad research and development (R&D) experience spanning organic chemistry, analytical chemistry, biochemistry, and biophysics. Demonstrated strengths in lead method development and direction, lab management, and staff/student training. Valued interdisciplinary team member with excellent writing and presentation skills, collaborative nature, talent for mastering new methods and techniques, and passion for creating novel technologies. Works efficiently in a fast paced interdisciplinary environment to deliver results to colleagues and collaborators. Bilingual in English and Turkish.

PhD Dissertation: Tuning Fluorescent Agents for Facilitating Biological Studies

MSc Thesis: Synthesis of 2-Aminopyrrole-3-carboxylates via Zinc Perchlorate Mediated Annulation of α-Cyano-δ-ketoesters with Amines

Links of Interest


  • Project Management
  • Product Development & Commercialization
  • Analytical Testing
  • Assay Design & Assay Development
  • Instrumentation
  • Troubleshooting
  • Lab Experience
  • GLP
  • Validation
  • Problem Solving
  • Team Leadership
  • Multi step synthesis
  • Grant & Proposal Writing

Recent Publications

  • Nazmiye B. Yapici, Y. Bi, P. Li, X. Chen, X. Yan, S. Mandalapu, M. Faucett, S. Jockusch, J. Ju, M. Gibson, W. J. Pavan and Lanrong Bi, Highly Stable and Sensitive Fluorescent Probes (LysoProbes) for Lysosomal Labeling and Tracking, Nature Scientific Reports, 2015, 8576.
  • Nazmiye B. Yapici, S.R. Mandalapu, Satya-Khuon, Teng-Leong Chew, Lanrong Bi, Determination of intracellular pH using sensitive, clickable fluorescent probe, Bioorg. Med. Chem. Lett., 2012, 2440.
  • Nazmiye B. Yapici, S. Jockusch, A. Moscatelli, S.R. Mandalapu, Y. Itagaki, D.K. Bates, S. Wiseman, K.M. Gibson, N. Turro, Lanrong Bi, New Rhodamine Nitroxide Based Fluorescent Probes for Intracellular Hydroxyl Radical Identification in Living Cells, Org. Lett., 2012, 50.
  • Ayhan S. Demir, M. Emrullahoglu, E. Pirkin, Nazmiye B. Akca, Darzens Reaction of Acyl Phosphonates with α-Bromo ketones: Selective Synthesis of cis- and trans- Epoxyphosphonates, J. Org. Chem, 2008, 8992.