Xuan Liu

Xuan Liu


Assistant Professor, Biomedical Engineering


The research of Dr. Xuan Liu’s laboratory focuses on developing novel optical imaging and sensing techniques for biomedical applications. One major area of our study is optical coherence tomography (OCT) which provides high resolution cross-sectional images of biological specimen in real-time. OCT has been used to help the diagnosis of various diseases in ophthalmology, cardiology and oncology. Currently, we are developing a manually scanned OCT system with a miniature probe. Moreover, we are also interested in extraction functional information from OCT images to characterize chemical and mechanical properties of biomedical specimens or synthetic biomedical materials.

 Dr. Liu received her B.S . and M.S. degrees from Tsinghua University, Beijing, China. She started to study in the Johns Hopkins University since 2007 and received her Ph.D degree in 2011. Before joining the faculty of Michigan Tech, Dr. Liu worked as post-doctoral fellow in the Johns Hopkins University.

Research Interests

  • Optical Coherence Tomography
  • Fiber optics for imaging and sensing
  • Signal processing
  • General physical problems in biophotonics

Selected Publications

  • X. Liu and J. U. Kang, "Depth-Resolved Blood Oxygen Saturation Assessment Using Spectroscopic Common-Path Fourier Domain Optical Coherence Tomography", IEEE Transactions on Biomedical Engineering 57, 2572 - 2575 (2010)
  • X. Liu and J. U. Kang, "Compressive SD-OCT: the application of compressed sensing in spectral domain optical coherence tomography," Opt. Express 18, 22010-22019 (2010)
  • X. Liu, M. Balicki, R. H. Taylor, and J. U. Kang, "Towards automatic calibration of Fourier-Domain OCT for robot-assisted vitreoretinal surgery," Opt. Express 18, 24331-24343 (2010)
  • X. Liu, Y. Huang and J. U. Kang, "Dark-field illuminated reflectance fiber bundle endoscopic microscope", J. Biomed. Opt. 16, 046003 (2011)
  • X. Liu, K. Zhang, Y. Huang, and J. U. Kang, "Spectroscopic-speckle variance OCT for microvasculature detection and analysis," Biomed. Opt. Express 2, 2995-3009 (2011)
  • X. Liu, I. I. Iordachita, X. He, R. H. Taylor, and J. U. Kang, "Miniature fiber-optic force sensor based on low-coherence Fabry-Pérot interferometry for vitreoretinal microsurgery," Biomed. Opt. Express 3, 1062-1076 (2012)
  • X. Liu, Y. Huang, and J. U. Kang, "Distortion-free freehand-scanning OCT implemented with real-time scanning speed variance correction," Opt. Express 20, 16567-16583 (2012)
  • Y. Huang, X. Liu, and J. U. Kang, "Real-time 3D and 4D Fourier domain Doppler optical coherence tomography based on dual graphics processing units," Biomed. Opt. Express 3, 2162-2174 (2012)
  • Y. Huang, X. Liu, C. Song, and J. U. Kang, "Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention, " Biomed. Opt. Express, under review
  • X. Liu, J. C. Ramella-Roman, Y. Huang, Y. Guo, and J. U. Kang, "Robust spectral-domain optical coherence tomography speckle model and its cross-correlation coefficient analysis, " Journal of the Optical Society of America A, under review
  • X. Liu , J. C. Ramella-Roman, Y. Huang, Y. Guo, and J. U. Kang, "Robust spectral-domain optical coherence model and its cross-correlation coefficient analysis, " J. Opt. Soc. Am. A 30 , 51-59 (2013)
  • X. Liu , Y. Huang, J. C. Ramella-Roman, S. Mathews, and J. U. Kang, "Quantitative transverse flow measurement speckle decorrelation analysis, " Opt. Lett. 38 , 805-807 (2013)
  • X. Liu and J. U. Kang, "Optimization of an angled fiber probe for common-path optical coherence tomography," 2660-2662 (2013)