Michigan Technological University

Department of Biomedical Engineering

Bruce P. Lee

Bruce P. Lee

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Assistant Professor, Biomedical Engineering

  • PhD, Biomedical Engineering, Northwestern University
  • MS, Biomedical Engineering, Northwestern University
  • BS, Chemical Engineering, Cornell University

Biography

The Lee group research is focused on applying biologically-inspired molecular designs with chemistry, polymer engineering and materials science principles in developing advanced and functional materials for various biomedical applications. Current projects include applying biomimetic structural designs to create tough hydrogels that can potentially function as tissue adhesives or extracellular matrices for tissue repair and regeneration, and coatings to control biointerface of biomaterials that can prevent non-specific absorption of proteins, cells, and bacteria.

Prior to joining Michigan Tech, Dr. Lee helped found a start-up company, Nerites Corporation, which aimed at commercializing biomimetic bioadhesive and antifouling technologies. Nerites Corporation was acquired by Kensey Nash Corporation in 2011.

Research Interests

  • Biomimetic, bio-inspired materials
  • Biointerface
  • Antimicrobial and antifouling coatings
  • Polymer chemistry
  • Nanotechnology
  • Tissue adhesives
  • Bruce P. Lee, Phillip B. Messersmith, Jacob N. Israelachvili, J. Herbert Waite. “Mussel-inspired adhesives and coatings”. Annual Review of Materials Research, 41, 99-132, (2011).
  • Michael Brodie, Laura Vollenweider, John L. Murphy, Fangmin Xu, Arinne Lyman, William D. Lew, Bruce P. Lee. “Biomechanical properties of Achilles tendon repair augmented with bioadhesive-coated scaffold”. Biomedical Materials, 6, 015014 (2011).
  • Niels Holten-Andersen, Matthew J. Harrington, Henrik Birkedal, Bruce P. Lee, Phillip B. Messersmith, Ka Yee C. Lee, J. Herbert Waite. “pH-induced mussel metal-ligand crosslinks yield self-healing polymer networks with near-covalent elastic moduli”. Proceedings of the National Academy of Sciences, 15, 2651-2655 (2011).
  • John L. Murphy, Laura Vollenweider, Fangmin Xu, Bruce P. Lee. “Adhesive performance of biomimetic adhesive-coated biologic scaffold”. Biomacromolecules, 11, 2976-2984 (2010).
  • Andrea Pechey, Chelsea N. Elwood, Geoffrey R. Wignall, Jeffrey L. Dalsin, Bruce P. Lee, Maaike Vanjecek, Ian Welch, Raymond Ko, Hassan Razvi, Peter A. Cadieux. “Anti-adhesive coating and clearance of device associated uropathogenic escherichia coli cystitis”. Journal of Urology, 182, 1628-1636 (2009).
  • Haeshin Lee, Bruce P. Lee, Phillip B. Messersmith. "A reversible wet/dry adhesive inspired by mussels and geckos". Nature, 448, 338-342 (2007). (Cover Article)

Issued Patents

  • Bruce P. Lee. “Biomimetic Compounds and Synthetic Methods Therefore”. US Patents 7,622,533 (issued 2009), 8,030,413 (issued 2011).
  • Jeffrey L. Dalsin, Bruce P. Lee, Laura Vollenweider, Sunil Silvary, John L. Murphy, Fangmin Xu, Amanda Spitz, Arinne Lyman. “Multi-Armed Catechol Compound Blends”. US Patent 8,119,742 (issued 2012).
  • Kenneth R. Shull, Murat Guvendiren, Phillip B. Messersmith, Bruce P. Lee. “Modified acrylic block copolymers for hydrogels and pressure sensitive wet adhesives”. US Patents 7,635,737 (issued 2009), 7,732,539 (issued 2010), 7,943,703 (issued 2011).

Biomedical Engineering

309 Minerals & Materials Engineering Bldg
1400 Townsend Drive
Houghton, MI 49931

Ph. 906-487-2772
Fax: 906-487-1717
Email: biomed@mtu.edu

Michigan Technological University

1400 Townsend Drive
Houghton, Michigan 49931-1295
906-487-1885

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