Guiliang Tang

Guiliang Tang


Professor, Biological Sciences

  • PhD, Weizmann Institute of Sciences, Israel, 2001


Recruitment: "One Graduate or Undergraduate Student Researcher in Computer Science is Needed to Do Research on Genome Browser (JBrowse) and RNA-seq on Hourly Pay" (Feb., 5, 2017)

One graduate or undergraduate student researcher in computer science will be recruited and paid hourly to work on installing JBrowse ( and RNA-seq using a Linux computer.  Interested students please contact Dr. Guiliang Tang (email:

Dr. Tang conducted his graduate research on the catabolic pathway of the essential amino acid lysine in the laboratory of Dr. Gad Galili at the Weizmann Institute of Sciences, Israel. He then moved to the laboratory of Dr. Phillip D. Zamore at the University of Massachusetts Medical School for his post-doctoral research on plant RNA interference (RNAi) and microRNA (miRNA) pathways. He established his independent Gene Suppression Laboratory at the University of Kentucky (UK) and became a tenured Associate Professor there. In October 2011, he moved from UK to Michigan Technological University (MTU) at the Michigan’s Upper Peninsula (U. P.) for a family reunion and enjoyed the first winter time with much outdoor activities with his wife and kids. In May 2016, he became a full Professor at MTU.

Links of Interest

Research Interests

  • Gene Silencing
  • RNA Interference (RNAi)
  • MicroRNA (miRNA)
  • RNA Silencing in Plant Germ Extract and Drosophila Embryo Lysate.
  • Fungal RNAi and microRNA
  • MicroRNA Technologies: Small Tandem Target mimic (STTM) and MicroRNA Array
  • Plant Electrophysiology in Plant microRNA STTM lines and Venus flytrap.

Recent Publications

  • Wanzhen LI, Yulong WANG, Jianyu ZHU, Zhangxun WANG, Guiliang TANG, Bo HUANG (2017)Differential DNA methylation may contribute to temporal and spatial regulation of gene expression and the development of mycelia and conidia in entomopathogenic fungus Metarhizium robertsii. Fungal Biology (Online) Read More
  • Jun Yan, Chunzhao Zhao, Jianping Zhou, Yu Yang, Pengcheng Wang, Xiaohong Zhu, Guiliang Tang, Ray A. Bressan, Jian-Kang Zhu (2016) The miR165/166 Mediated Regulatory Module Plays Critical Roles in ABA Homeostasis and Response in Arabidopsis thaliana. Plos Genetics DOI:10.1371/journal.pgen.1006416. Read More
  • Yang Chen, Dong-Jie Zhao, Zi-Yang Wang, Zhong-Yi Wang, Guiliang Tang, and Lan Huang (2016) Plant Electrical Signal Classification Based on Waveform Similarity. Algorithms 9(4), 70. Read More
  • Lina Shi, Xiaoqing Tang, Guiliang Tang (2016) GUIDE-seq to Detect Genome-wide Double-Stranded Breaks in Plants. Trends in Plant Science 21(10): 815-818. Read More
  • Sachin Teotia, Deepali Singh, Xiaoqing Tang, Guiliang Tang (2016) Essential RNA-Based Technologies and Their Applications in Plant Functional Genomics. Trends in Biotechnology. 34(2):106-23. Read More
  • Wu X, Ding D, Shi C, Xue Y, Zhang Z, Tang G, Tang J. (2016) microRNA-dependent gene regulatory networks in maize leaf senescence. BMC Plant Biol. 16:73. doi: 10.1186/s12870-016-0755-y. Read More
  • Wang X, Chen L, Jin H, Wang S, Zhang Y, Tang X, Tang G (2016) Screening miRNAs for early diagnosis of colorectal cancer by small RNA deep sequencing and evaluation in a Chinese patient population. OncoTargets and Therapy. 9: 1159-1166. Read More
  • Zhang Z, Wu X, Shi C, Wang R, Li S, Wang Z, Liu Z, Xue Y, Tang G, Tang J. (2016) Genetic dissection of the maize kernel development process via conditional QTL mapping for three developing kernel-related traits in an immortalized F2 population.Mol Genet Genomics. 291(1):437-54. Read More

Recent Funding

  • Inactivation of microRNAs in Crop Plants Using Short Tandem Target Mimic (STTM) Technology. Award Number:1340001; Principal Investigator:Guiliang Tang; Co-Principal Investigator:Xuemei Chen, Wenbo Ma, Harold Trick, Hairong Wei; Organization:Michigan Technological University;NSF Organization:IOS Award Date:06/01/2014; Award Amount:$2,499,979.00.

Research Projects

  • Inactivation of microRNAs in Crop Plants Using Short Tandem Target Mimic (STTM) Technology.
  • EAGER: RNAi Gene Discovery Tool to Randomly Generate Dominant Mutant Pools in Plants