Guiliang Tang

Guiliang Tang

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Associate Professor, Biological Sciences

  • PhD, Weizmann Institute of Sciences, Israel, 2001

Biography

Dr. Tang conducted his graduate research on the catabolic pathway of the essential amino acid lysine in the laboratory of Dr. Gad Galili at the Weizmann Institute of Sciences, Israel. He then moved to the laboratory of Dr. Phillip D. Zamore at the University of Massachusetts Medical School for his post-doctoral research on plant RNA interference (RNAi) and microRNA (miRNA) pathways. He established his independent Gene Suppression Laboratory at the University of Kentucky (UK) and became a tenured Associate Professor there. In October 2011, he moved from UK to Michigan Technological University (MTU) at the Michigan’s Upper Peninsula (U. P.) for a family reunion and enjoyed the first winter time with much outdoor activities with his wife and kids.

Links of Interest

Research Interests

  • Gene Silencing
  • RNA Interference (RNAi)
  • MicroRNA (miRNA)
  • Wheat Germ Extract
  • Drosophila Embryo Lysate, Arabidopsis, and other Plant Systems
  • MicroRNA Technologies: Small Tandem Target mimic (STTM) and MicroRNA Array

Recent Publications

  • Zhenying Cai, Jingjing Liu, Haijiao Wang, Cangjing Yang, Yuxiao Chen, Yongchi Li, Shanjin Pan, Rui Dong, Guiliang Tang, Juan de Dios Barajas-Lopez, Hiroaki Fujii, and Xuelu Wang (2014) GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s in Arabidopsis. Proc Natl Acad Sci U S A. 2014 Jun 13. pii: 201316717. [Epub ahead of print] Read More
  • James Wong, Lei Gao, Yang Yang, Jixian Zhai, Siwaret Arikit, Yu Yu, Shuyi Duan, Vicky Chan, Qin Xiong, Jun Yan, Shengben Li, Renyi Liu, Yuanchao Wang, Guiliang Tang, Blake C. Meyers, Xuemei Chen and Wenbo Ma (2014) Roles of Small RNAs in Soybean Defense against Phytophthora sojae Infection. Plant J. 2014 Jun 18. doi: 10.1111/tpj.12590. [Epub ahead of print] Read More
  • Chi M, Bhagwat B, Lane WD, Tang G, Su Y, Sun R, Oomah BD, Wiersma PA, Xiang Y. (2014) Reduced polyphenol oxidase gene expression and enzymatic browning in potato (Solanum tuberosum L.) with artificial microRNAs. BMC Plant Biol. 11;14(1):62. Read More
  • Tang G and Tang X. (2013) Short Tandem Target Mimic: A Long Journey to the Engineered Molecular Landmine for Selective Destruction/Blockage of microRNAs in Plants and Animals. Journal of Genetics and Genomics. 40 (6): 291–296. Read More
  • Bhagwata B, Chia M, Su L, Tang H, Tang G., Xiang Y. (2013) An in vivo Transient Expression System Can Be Applied for Rapid and Effective Selection of Artificial microRNA Constructs for Plant Stable Genetic Transformation. Journal of Genetics and Genomics. 40(5): 261-70. Read More
  • Tang G*, Yan J, Gu Y, Qiao M, Fan R, Mao Y, Tang X*. (2012) Construction of short tandem target mimic (STTM) to block the functions of plant and animal microRNAs. Methods 58(2):118-25.(*Corresponding authors) Read More
  • Yan J, Gu Y, Jia X, Kang W, Pan S, Tang X, Chen X, Tang G. (2012) Effective small RNA destruction by the expression of a short tandem target mimic in Arabidopsis. Plant Cell. 24(2):415-27. Read More
  • Lewis RW, Tang G, McNear DH Jr. (2012) Morphological and genetic changes induced by excess Zn in roots of Medicago truncatula A17 and a Zn accumulating mutant.BMC Res Notes. 5(1):657 Read More
  • Ren L. and Tang G. (2012) Identification of sucrose-responsive microRNAs reveals sucrose-regulated copper accumulations in an SPL7-dependent and independent manner in Arabidopsis thaliana. Plant Science, 187: 59-68 Read More
  • Dianwei Han, Jun Zhang, and Guiliang Tang (2012) MicroRNAfold: pre-microRNA secondary structure prediction based on Modified NCM model with thermodynamics-based scoring strategy. International Journal of Data Mining and Bioinformatics 6(3):272-91 Read More
  • Iyer NJ, Jia X, Sunkar R, Tang G, Mahalingam R. (2012) microRNAs responsive to ozone-induced oxidative stress in Arabidopsis thaliana. Plant Signal Behav 7(4):484 - 491. Read More
  • Lijuan Ji, Xigang Liu, Jun Yan, Wenming Wang, Rae Eden Yumul, Yu Ju Kim, Thanh Theresa Dinh, Jun Liu, Xia Cui, Binglian Zheng, Manu Agarwal, Chunyan Liu, Xiaofeng Cao, Guiliang Tang, and Xuemei Chen* (2011) ARGONAUTE10 and ARGONAUTE1 Regulate the Termination of Floral Stem Cells through Two microRNAs in Arabidopsis. PLoS Genet. 7(3):e1001358. Epub 2011 Mar 31. Read More
  • Tang X, Tang X, Gal J, Kyprianou N, Zhu H, Tang G. (2011) Detection of microRNAs in prostate cancer cells by microRNA array. Methods Mol Biol. 732:69-88. Read More
  • Xiaoyun Jia, Jun Yan, and Guiliang Tang (2011) MicroRNA-mediated DNA methylation in plants. Frontiers in Biology 6(2):133-139 Read More
  • Dianwei Han, Guiliang Tang, and Jun Zhang (2011) A Parallel Strategy for Predicting the Secondary Structure of Polycistronic MicroRNAs. Int. J.Bioinformatics Research and Applications (In press)
  • Guiliang Tang (2010) Plant microRNAs: An insight into their gene structures and evolution. Seminars in Cell and Developmental Biology 21:782-789. Read More
  • Wang WX, Wilfred BR, Madathil SK, Tang G, Hu Y, Dimayuga J, Stromberg AJ, Huang Q, Saatman KE, Nelson PT (2010) MiR-107 Regulates Granulin/Progranulin with Implications for Traumatic Brain Injury and Neurodegenerative Disease. Am J Pathol. 177(1):334-45 Read More

Recent Funding

  • Inactivation of microRNAs in Crop Plants Using Short Tandem Target Mimic (STTM) Technology. Award Number:1340001; Principal Investigator:Guiliang Tang; Co-Principal Investigator:Xuemei Chen, Wenbo Ma, Harold Trick, Hairong Wei; Organization:Michigan Technological University;NSF Organization:IOS Award Date:06/01/2014; Award Amount:$2,499,979.00.

Research Projects

  • Inactivation of microRNAs in Crop Plants Using Short Tandem Target Mimic (STTM) Technology.
  • EAGER: RNAi Gene Discovery Tool to Randomly Generate Dominant Mutant Pools in Plants