—Can we identify genes regulating traits? --- Yes, we can.
Assistant Professor—SFRES
Adjunct Assistant Professor—CS
- PhD, Plant Molecular Biology, University of Hawaii at Manoa
- MS, Computer Science, University of Chicago
- MS, Forest Genetics, Beijing Forestry University
- BS, Agricultural Sciences, Beijing Forestry University
Yes, we can.
I am exploring the possibility of identifying genes regulating biological traits via systems biology approaches. We achieve this goal through combinatorial approaches: (1) Designing very efficient biological experiments to yield information-enriched gene expression data sets. (2) Performing gene reduction to identify major regulators controlling traits via complex data analysis. (3) Construction of local regulatory networks controlling a trait. We have developed the algorithms and software pipelines for accurately identifying transcription factors controlling a trait with 50-100 % accuracy. I am in general interested in identifying genes regulating the following traits: (1) Wood productivity and quality. (2) Resistance to disease and pest. (3) Biomass production. However, identification of genes regulating any of agriculturally important traits interests me.
Links of Interest
Areas of Expertise
- Identification of genes regulating traits via systems biology approaches
- Gene expression data analysis
- Gene network construction and decomposition
- Developing software for mining large-scale biological data
- Genomics of wood formation